Comments on: How to calculate System Suitability in Chromatography https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/ Experience Beyond Books Mon, 26 Feb 2024 10:58:10 +0000 hourly 1 https://wordpress.org/?v=6.7.2 By: Ankit Khurana https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-256488 Mon, 26 Feb 2024 10:58:10 +0000 https://lab-training.com/?p=8202#comment-256488 In reply to samadhan patil.

Dear Samadhan,

The gradual decrease in retention time (RT) of both sample and standard on the GC column could be attributed to factors such as column degradation, contamination, changes in column temperature, or issues with the injection system

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By: samadhan patil https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-256474 Sat, 24 Feb 2024 10:49:52 +0000 https://lab-training.com/?p=8202#comment-256474 In reply to Dr. Deepak Bhanot.

Hello sir good afternoon
My question is the GC column is decreasing the RT OF sample & standard on day by day so what are the main reason behind. kindly reply

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By: carlos https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-204865 Sat, 11 Jun 2022 16:44:13 +0000 https://lab-training.com/?p=8202#comment-204865 Magistral

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By: Priyal Bambhaniya https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-146928 Tue, 14 Jul 2020 03:56:11 +0000 https://lab-training.com/?p=8202#comment-146928 Fill your response that both compounds 1 and 2 satisfy ICH guidliness for asymmetric factor and tailing factor. If your answer is yes or no than will provide the reason.

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By: suresh singaram https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-137643 Mon, 19 Aug 2019 11:57:58 +0000 https://lab-training.com/?p=8202#comment-137643 what is the void volume role in the empower calculation. and can you give clear definition of void volume

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By: Dr. Saurabh Arora https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-135718 Sun, 07 Jul 2019 14:50:32 +0000 https://lab-training.com/?p=8202#comment-135718 In reply to Basha.

Hi, having 6 points increase the statistical power and is generally prefered.

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By: Basha https://lab-training.com/how-to-calculate-system-suitability-in-chromatography/#comment-134650 Tue, 25 Jun 2019 22:59:50 +0000 https://lab-training.com/?p=8202#comment-134650 In reply to Dr. Deepak Bhanot.

There is a concept of 6 sigma and 3 sigma where in we need minimum 3-points for the agreement
i mean to see that your system is precised enough for the analysis u need to meet the criteria of RSD either with 3-points or with 5-6 points

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